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macrophage migration inhibitory factor*******Discovered in the late 1960s as a product of activated T cells, the cytokine macrophage migration inhibitory factor (MIF) has been discovered recently to carry out .
Macrophage Migration-Inhibitory Factors. For more than a quarter of a century, macrophage migration inhibitory factor (MIF) has been a mysterious cytokine. In recent years, MIF . Macrophage migration inhibitory factor (MIF) was originally identified in the culture medium of activated T lymphocytes as a soluble factor that inhibited the .Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine encoded within a functionally polymorphic genetic locus. MIF was initially recognized as a . The role of macrophage migration inhibitory factor (MIF) in autoimmunity is underscored by data showing that common functional polymorphisms in MIF are associated with disease susceptibility or.
macrophage migration inhibitory factor macrophage migration inhibition factor 3.30.429.10 Macrophage Migration Inhibitory Factor 1 hit InterPro View protein in InterPro IPR001398 Macrophage_inhib_fac IPR019829 Macrophage_inhib_fac_CS IPR014347 Tautomerase/MIF_sf PANTHER PTHR11954 D-DOPACHROME DECARBOXYLASE 1 . Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine encoded within a functionally polymorphic genetic locus. MIF was initially recognized as a cytokine generated by activated T cells, but in recent days it has been identified as a multipotent key cytokine secreted by many other cell types involved in . Macrophage migration inhibitory factor (MIF) as a soluble pro-inflammatory cytokine has become one of the most puzzling regulators of innate and adaptive immune responses. In myeloma, MIF was found to be significantly higher in MM cells from relapsed patients than those responding to the treatment.macrophage migration inhibition factor 巨噬细胞迁移抑制因子 (macrophage migration inhibitory factor, MIF)是一种多功能蛋白, 既可以作为细胞因子发挥促炎作用, 又具有类似趋化因子的功能, 调节其他促炎因子产生。. MIF的一个重要特性是具有 D -多巴色素互变异构酶、苯丙酮酸盐互变异构酶以及硫醇蛋白氧化 .macrophage migration inhibitory factor Macrophage migration inhibitory factor (MIF), a T-cell-derived factor, was firstly thought to inhibit the migration of macrophages in experiments designed to characterize delayed-type hypersensitivity and hence derived its name in 1966. [] Later, the molecule was . Macrophage migration inhibitory factor (MIF) was originally identified in the culture medium of activated T lymphocytes as a soluble factor that inhibited the random migration of macrophages. MIF is now recognized to be a multipotent cytokine involved in the regulation of immune and inflammatory responses. Moreover, the pivotal .
Macrophage migration inhibitory factor (MIF) was identified nearly four decades ago as one of the first cytokines discovered 〚1〛, 〚2〛. MIF was initially described as an immune activity isolated from the supernatants of T lymphocytes and was found to inhibit the random migration of macrophages.
Macrophage migration inhibitory factor (MIF) emerged in recent years as an important inflammation mediator, playing a prominent role in the pathogenesis of various types of malignant neoplasm. MIF is a glycoprotein that presents a wide spectrum of biological activities and exerts a complex interaction with various cellular signaling .
Macrophage migration inhibitory factor (MIF) functions as a pleiotropic protein, participating in inflammatory and immune responses. MIF was originally discovered as a lymphokine involved in delayed hypersensitivity and various macrophage functions, including phagocytosis, spreading, and tumoricidal activity. Macrophage migration inhibitory factor (MIF), a mediator of the innate immune system, is involved in many inflammatory processes and related disorders, including obesity and diabetes mellitus 7,8 . Macrophage migration inhibitory factor (MIF) is a pluripotent pro-inflammatory cytokine and is related to acute and chronic inflammatory responses, immune disorders, tumors, and other diseases . Introduction Macrophage migration inhibitory factor (MIF) was originally discovered in 1966 as a lymphokine derived from activated T cells during delayed-type hypersensitivity (Bloom and Bennett, 1966; David, 1966), exhibiting inhibition function of macrophage migration.), exhibiting inhibition function of macrophage migration.
Macrophage migration inhibitory factor (MIF) is a conserved cytokine found as a homotrimer protein. It is found in a wide spectrum of cell types in the body including neuronal and non-neuronal cells. MIF is implicated in several biological processes; chemo-attraction, cytokine activity, and receptor . Abstract. Macrophage migration inhibitory factor (MIF) is an upstream regulator of the immune response whose dysregulation is tied to a broad spectrum of inflammatory and proliferative disorders. As its complex signaling pathways and pleiotropic nature have been elucidated, it has become an attractive target for drug discovery.
A tautomerase-null macrophage migration-inhibitory factor (MIF) gene knock-in mouse model reveals that protein interactions and not enzymatic activity mediate MIF-dependent growth regulation. Mol Cell Biol, 2009. 29 (7): p. 1922–32. [PMC free article] [] []
This volume looks at--and discusses the techniques of--a range of areas in biology in which macrophage migration inhibitory factor (MIF) is studied. Topics covered in this book include methods to quantify MIF in cell supernatants and human samples, using ELISA and western blot; detection and analysis of intracellular MIF using flow cytometry .Macrophage migration inhibitory factor (MIF) is a ubiquitous protein that is found in virtually all cells. Its precise function in the majority of cells is not known, but studies performed over the last decade indicate that it is a critical upstream regulator of the innate and acquired immune response. MIF is released under a variety of .
Macrophage migration inhibitory factor (MIF) as a therapeutic target for rheumatoid arthritis and systemic lupus erythematosus Expert Opin. Ther. Targets , 23 ( 2019 ) , pp. 733 - 744 CrossRef View in Scopus Google Scholar
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macrophage migration inhibitory factor|macrophage migration inhibition factor